2016 Who Global Guidelines For The Prevention Of Surgical Site Infection: A New Step To Improve Patients’ Safety Before, During And After Surgery
Guidelines Paper Review

2016 Who Global Guidelines For The Prevention Of Surgical Site Infection: A New Step To Improve Patients’ Safety Before, During And After Surgery

Vincenzo Davide Palumbo, Antonio Bruno, Benedetto Di Trapani, Giovanni Tomasello

ABSTRACT
Surgical site infections (SSIs) are among the most preventable health-care-associated infections and are a substantial burden to health-care systems and service payers worldwide in terms of patient morbidity, mortality, and additional costs. SSI prevention is complex and requires the integration of a range of measures before, during, and after surgery. No international guidelines are available and inconsistencies in the interpretation of evidence and recommendations of national guidelines have been identified. Given the burden of SSIs worldwide, the numerous gaps in evidence-based guidance, and the need for standardisation and a global approach, WHO decided to prioritise the development of evidence-based recommendations for the prevention of SSIs. The guidelines take into account the balance between benefits and harms, the evidence quality, cost and resource use implications, and patient values and preferences. On the basis of systematic literature reviews and expert consensus, we present 23 recommendations on preoperative, intraoperative and postoperative preventive measures. The WHO recommendations were developed with a global perspective and they take into account the balance between benefits and harms, the evidence quality level, cost and resource use implications, and patient values and preferences.

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